3-Formyl-1H-indazole-5-carboxylic acid

3-Formyl-1H-indazole-5-carboxylic acid - Names and Identifiers

Name	3-Formyl-1H-indazole-5-carboxylic acid
Synonyms	3-ForMyl-1H-indazole-5-carboxylic 3-Formyl-5-indazole carbocylic acid 3-Formyl-1H-indazole-5-carboxylic acid 1H-Indazole-5-carboxylicacid,3-forMyl- 3-formyl-2H-indazole-5-carboxylic acid 1H-Indazole-5-carboxylic acid, 3-formyl-
CAS	885519-98-2
InChI	InChI=1S/C9H6N2O3/c12-4-8-6-3-5(9(13)14)1-2-7(6)10-11-8/h1-4H,(H,10,11)(H,13,14)

3-Formyl-1H-indazole-5-carboxylic acid - Physico-chemical Properties

Molecular Formula	C9H6N2O3
Molar Mass	190.16
Density	1.594±0.06 g/cm3(Predicted)
Boling Point	521.9±30.0 °C(Predicted)
pKa	3.76±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

3-Formyl-1H-indazole-5-carboxylic acid - Introduction

Acid is an organic compound with the chemical formula C10H6N2O3. The following is a description of its nature, use, formulation and safety information:

Nature:
1. Appearance: acid is a white crystalline solid.
2. Solubility: It is almost insoluble in water, but soluble in organic solvents such as ethanol and dimethyl sulfoxide.
3. melting point: its melting point is about 210-216 degrees Celsius.
4. Stability: It is relatively stable at room temperature, but too high temperature should be avoided.

Use:
1. Chemical intermediates: acid can be used as intermediates for the synthesis of other organic compounds, such as drugs, dyes, etc.
2. drug research: the compound is used in the field of biomedical research, especially in the treatment of cancer.

Preparation Method:
There are many methods for preparing acid. One of the commonly used methods is the base-catalyzed reaction of aldehyde compounds and indazole. In the specific operation, the aldehyde compound is first reacted with pyrrole under the catalysis of a base to obtain the aldehyde compound. Then, the aldehyde compound is reacted with sodium carbonate under acidic conditions to obtain acid.

Safety Information:
1. The toxicity of acid has not been studied in detail, so appropriate protective measures should be taken when using it, such as wearing protective gloves and glasses.
2. it should be placed in a dry, well-ventilated place, away from fire and oxidant.
3. if ingestion or contact with skin, eyes and other parts, please rinse immediately with plenty of water, and seek medical help.

Please note that the above is only some basic information. If you need more detailed understanding and use, please refer to relevant literature and safety manuals, or consult a professional chemist.

Last Update：2024-04-09 20:49:11